Opportunity Information: Apply for RFA AG 24 020
This NIH funding opportunity (RFA-AG-24-020) supports a two-phase R61/R33 grant to build and run a networking and research infrastructure project focused on comparative studies of aging across humans and nonhuman primates. The central goal is not to fund a single standalone biology study, but to strengthen the field by creating the connections, shared resources, and coordinated capabilities needed to accelerate research on why different primate species (including humans) vary so much in lifespan, life history patterns, and other aging-related outcomes. A major emphasis is on improving the prospects for translating insights from comparative primate research into strategies that could eventually inform or inspire interventions to improve human health during aging. Clinical trials are not allowed under this announcement.
The project concept is explicitly “networking/infrastructure,” meaning applicants are expected to propose an organized effort that enables other scientific work to move faster and be more comparable across sites, species, or datasets. In practical terms, that kind of effort typically includes building collaborative networks among investigators and primate resources, developing shared standards or harmonized measures, improving access to data or biospecimens, creating platforms that make cross-species comparisons more rigorous, and setting up processes that help the community identify the most promising translational directions. The scientific theme is comparative research on determinants of differences in aging and longevity across primates, including the factors that shape life spans, life histories, and aging phenotypes, and how those determinants might point toward actionable targets for human aging interventions. Even though the FOA is oriented toward translation, it is aimed at upstream enabling work rather than testing interventions in people.
The mechanism is an R61/R33 phased innovation award. The R61 phase is generally used to launch and demonstrate the early feasibility of the proposed approach, while the R33 phase supports expansion once clearly defined milestones are met. For applicants, that structure usually means the application should lay out concrete, measurable deliverables for the early stage (for example, standing up a functioning network, establishing governance and operating procedures, launching pilot coordination activities, releasing shared tools or resources, or demonstrating successful multi-site data harmonization) and then a credible plan for scaling or sustaining those efforts in the later stage. Because the award is milestone-driven, the proposal needs a strong management plan, clear success criteria, and a credible strategy for maintaining momentum and utility to the broader research community.
Eligibility is broad and includes many kinds of U.S.-based organizations: state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education when listed in those categories); for-profit organizations other than small businesses; small businesses; and other eligible entities. The FOA also calls out additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, Tribally Controlled Colleges and Universities, faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
Foreign organizations and foreign institutions (non-domestic, non-U.S. entities) are not eligible to apply as the primary applicant. However, non-domestic components of U.S. organizations are allowed, and “foreign components” as defined in the NIH Grants Policy Statement are permitted. In other words, the applicant organization must be U.S.-based and eligible, but the work may still incorporate certain international collaborations or elements when they meet NIH’s definition and requirements for foreign components.
The awarding agency is the National Institutes of Health, and the activity category is health (CFDA 93.866). The original application due date listed for this opportunity was September 27, 2023. The provided source information does not list an award ceiling or the expected number of awards, so applicants would need to consult the full FOA text or NIH notices for budget expectations, anticipated funding levels, and any institute-specific priorities tied to NIA/NIH aging research. Overall, the announcement is aimed at building field-level capacity: creating the infrastructure and collaborative networks that make it easier to do high-quality, comparative primate aging research and to connect those findings to plausible paths toward human intervention development, without conducting clinical trials under this grant.Apply for RFA AG 24 020
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Networking/Infrastructure Project for Research on Determinants of Differences Among Human and Nonhuman Primate Species in Life Spans, Life Histories, and Other Aging Related Outcomes, and Prospects for Translation (R61/R33 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2023-02-10.
- Applicants must submit their applications by 2023-09-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Comparative Research on Determinants of Differences Among Human and Nonhuman Primate Species in Life Spans, Life Histories, and Other Aging-Related Outcomes, and Prospects for Translation (R01 Clinical Trial Not Allowed) Apply for RFA AG 24 019 Funding Number: RFA AG 24 019 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| IDeA Networks of Biomedical Research Excellence (INBRE) (P20 Clinical Trial Optional) Apply for PAR 23 100 Funding Number: PAR 23 100 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Expand Family Planning and Sexual and Reproductive Health Activity (ExpandPF) Apply for RFI 624 23 00001 Funding Number: RFI 624 23 00001 Agency: West Africa USAID-Ghana Category: Health Funding Amount: $45,000,000 |
| Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional) Apply for PAR 23 099 Funding Number: PAR 23 099 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Advancing HIV/AIDS Research within the Mission of the NIDCD (R21 Clinical Trial Optional) Apply for PAR 23 106 Funding Number: PAR 23 106 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Community Level Interventions to Improve Minority Health and Reduce Health Disparities (R01 - Clinical Trial Optional) Apply for RFA MD 23 004 Funding Number: RFA MD 23 004 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| AHRQ Improving Diagnostic Safety in Ambulatory Care: Strategies and Preventions (R18) Apply for RFA HS 23 011 Funding Number: RFA HS 23 011 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $500,000 |
| Dissemination and Implementation of Equity-Focused Evidence-Based Interventions in Healthcare Delivery Systems (R18) Apply for RFA HS 23 002 Funding Number: RFA HS 23 002 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $2,500,000 |
| AHRQ Understanding and Improving Diagnostic Safety in Ambulatory Care: Incidence and Contributing Factors (R01) Apply for RFA HS 23 010 Funding Number: RFA HS 23 010 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $500,000 |
| Supporting the Management of Substance Use Disorders in Primary Care and other Ambulatory Settings (R18) Apply for RFA HS 23 005 Funding Number: RFA HS 23 005 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $625,000 |
| Genomics Centers for Infectious Diseases (U19 Clinical Trial Not Allowed) Apply for RFA AI 23 015 Funding Number: RFA AI 23 015 Agency: National Institutes of Health Category: Health Funding Amount: $2,850,000 |
| Using Secondary Data Analysis to Determine Whether Preventive Interventions Implemented Earlier in Life Reduce Suicide Risk (U01 Clinical Trial Not Allowed) Apply for RFA MH 23 275 Funding Number: RFA MH 23 275 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Research Network to Promote Multidisciplinary Mechanistic and Translational Studies of Sickle Cell Disease Pain (U24, Clinical Trial Optional) Apply for RFA AT 24 001 Funding Number: RFA AT 24 001 Agency: National Institutes of Health Category: Health Funding Amount: $600,000 |
| Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76 Independent Clinical Trial Not Allowed) Apply for RFA AG 24 014 Funding Number: RFA AG 24 014 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| Paul B. Beeson Emerging Leaders Career Development Award in Aging (K76 Clinical Trial Required) Apply for RFA AG 24 015 Funding Number: RFA AG 24 015 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| NIMH Short Courses for Mental Health Related Research (R25 -Independent Clinical Trial Not Allowed) Apply for PAR 23 265 Funding Number: PAR 23 265 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed) Apply for PAR 23 263 Funding Number: PAR 23 263 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| NIMH Research Education Programs for Psychiatry Residents (R25- Independent Clinical Trial Not Allowed) Apply for PAR 23 266 Funding Number: PAR 23 266 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Roybal Centers for Translational Behavioral Research on Dementia Care, Caregiver Support, and Prevention of Alzheimers Disease and Related Dementias (AD/ADRD) (P30 Clinical Trial Required) Apply for RFA AG 24 007 Funding Number: RFA AG 24 007 Agency: National Institutes of Health Category: Health Funding Amount: $750,000 |
| Edward R. Roybal Coordinating Center (R24 - Clinical Trial Not Allowed) Apply for RFA AG 24 008 Funding Number: RFA AG 24 008 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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