Opportunity Information: Apply for RFA HG 20 008
The National Institutes of Health (NIH) offered this funding opportunity to create and run a Mendelian Genomics Data Coordinating Center (MGDCC) that would serve as the central coordination hub for the Mendelian Genomics Research Consortium. The award mechanism is a U24 cooperative agreement, which generally means NIH expects substantial involvement during the project period, with ongoing coordination between the awardee and NIH program staff. The focus is on infrastructure and program-wide coordination rather than running a clinical trial, and the announcement explicitly states "Clinical Trial Not Allowed."
At its core, the MGDCC is meant to make Mendelian genomics outputs easier to share, find, and use across the broader research community. A major responsibility is managing the release of data and research findings generated by consortium-funded projects. That includes handling the practical details of data dissemination, promoting consistent and timely sharing, and helping ensure that data and results are distributed in a way that maximizes downstream value for other investigators. The opportunity also emphasizes program outreach, meaning the center is expected to communicate actively with stakeholders and the wider scientific community so that consortium resources and discoveries are visible, accessible, and actually used.
Beyond data release and outreach, the center is tasked with coordinating the logistics that keep a multi-site consortium functioning smoothly. This includes supporting working groups, organizing and facilitating meetings, and generally providing the administrative and operational backbone needed for collaborative science across multiple teams. In practice, that kind of role typically involves setting up communication channels, maintaining schedules and deliverables, tracking action items, standardizing workflows where helpful, and ensuring that consortium participants have the structure needed to move shared priorities forward.
A distinctive feature of this program is that the MGDCC would also oversee the consortium's Opportunity Fund. The intent of this fund is to provide rapid-turnaround, short-term support for functional follow-up studies that build directly on program findings. In other words, when the consortium identifies a promising gene, variant, or Mendelian disease signal, the Opportunity Fund is designed to quickly enable targeted experiments or analyses that validate and extend those discoveries. The coordinating center would manage this process, which implies responsibilities like running solicitations or internal competitions (as defined by the program), coordinating review or selection workflows, issuing and tracking awards, and monitoring progress to ensure the funds achieve their intended purpose.
The opportunity falls under the Health funding activity category (CFDA 93.172) and was posted as a discretionary funding opportunity. While the source text does not specify an award ceiling or the number of expected awards, the structure and responsibilities indicate NIH was seeking an organization with strong capabilities in data coordination, consortium operations, and grants or sub-award style management for the Opportunity Fund component.
Eligibility is broad. Standard eligible applicants listed include various levels of government (state, county, city or township, and special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, tribal organizations that are not federally recognized governments, public housing/Indian housing authorities, nonprofits (both 501(c)(3) and non-501(c)(3), excluding institutions of higher education when specified), for-profit organizations other than small businesses, and small businesses. The announcement also calls out additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, non-U.S. (foreign) organizations, regional organizations, and U.S. territories or possessions. This breadth signals NIH wanted to allow a wide range of potential coordinating entities, including academic, nonprofit, governmental, and international organizations, as long as they could credibly deliver the coordination, data-sharing, outreach, and rapid-funding functions described.
Key administrative details from the listing include the funding opportunity title "Mendelian Genomics Data Coordinating Center (U24 Clinical Trial Not Allowed)," funding opportunity number RFA HG 20 008, agency NIH, and an original closing date of July 15, 2020, with a creation date of January 13, 2020.Apply for RFA HG 20 008
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Mendelian Genomics Data Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172.
- This funding opportunity was created on 2020-01-13.
- Applicants must submit their applications by 2020-07-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is this NIH funding opportunity about?
This opportunity supports the creation and operation of a Mendelian Genomics Data Coordinating Center (MGDCC). The center is intended to serve as the central coordination hub for the Mendelian Genomics Research Consortium, with a strong emphasis on data coordination, consortium logistics, and program-wide outreach.
What is the official funding opportunity title?
The title is "Mendelian Genomics Data Coordinating Center (U24 Clinical Trial Not Allowed)."
What is the funding opportunity number?
The funding opportunity number is RFA HG 20 008.
Which agency is offering this opportunity?
The agency is the National Institutes of Health (NIH).
What type of award mechanism is used?
The award mechanism is a U24 cooperative agreement.
What does it mean that this is a U24 cooperative agreement?
A U24 cooperative agreement generally means NIH expects substantial involvement during the project period. This typically includes ongoing coordination and partnership between the awardee and NIH program staff.
Is a clinical trial allowed under this opportunity?
No. The announcement explicitly states "Clinical Trial Not Allowed."
What is the primary purpose of the Mendelian Genomics Data Coordinating Center (MGDCC)?
The MGDCC is meant to make Mendelian genomics outputs easier to share, find, and use across the broader research community. The focus is on infrastructure and program-wide coordination rather than conducting clinical research activities like clinical trials.
What are the core responsibilities related to data and findings?
A major responsibility is managing the release of data and research findings generated by consortium-funded projects. This includes handling practical details of data dissemination, promoting consistent and timely sharing, and helping ensure data and results are distributed in ways that maximize value for other investigators.
Does the opportunity emphasize outreach and communications?
Yes. The opportunity emphasizes program outreach, meaning the center is expected to communicate actively with stakeholders and the wider scientific community so consortium resources and discoveries are visible, accessible, and used.
What kinds of consortium coordination activities are expected?
The center is expected to coordinate logistics that support a multi-site consortium. This includes supporting working groups, organizing and facilitating meetings, and providing the administrative and operational backbone needed for collaboration across multiple teams.
What does "administrative and operational backbone" typically involve for a consortium?
Based on the description, this can include setting up communication channels, maintaining schedules and deliverables, tracking action items, standardizing workflows where helpful, and ensuring consortium participants have structure to move shared priorities forward.
What is the Opportunity Fund mentioned in this announcement?
The Opportunity Fund is a consortium component intended to provide rapid-turnaround, short-term support for functional follow-up studies that build directly on program findings.
What kinds of projects are supported by the Opportunity Fund?
The Opportunity Fund is intended to quickly enable targeted experiments or analyses that validate and extend discoveries, such as when the consortium identifies a promising gene, variant, or Mendelian disease signal.
What role does the MGDCC play in managing the Opportunity Fund?
The MGDCC would oversee the Opportunity Fund and manage the associated process. This implies responsibilities such as running solicitations or internal competitions (as defined by the program), coordinating review or selection workflows, issuing and tracking awards, and monitoring progress to ensure funds achieve their intended purpose.
What is the funding activity category and CFDA number?
The listing places this opportunity under the Health funding activity category with CFDA 93.172.
Was this posted as a discretionary funding opportunity?
Yes. It was posted as a discretionary funding opportunity.
Does the provided information specify an award ceiling?
No. The source text does not specify an award ceiling.
Does the provided information specify the number of expected awards?
No. The source text does not specify the number of expected awards.
What kinds of organizational capabilities does NIH appear to be seeking?
From the described structure and responsibilities, NIH appears to be seeking an organization with strong capabilities in data coordination and dissemination, consortium operations (meetings, working groups, multi-site logistics), outreach, and grants or sub-award style management to administer the Opportunity Fund component.
Who is eligible to apply?
Eligibility is broad and includes many organization types across government, academia, nonprofit, for-profit, small business, tribal entities, and international organizations, as listed in the announcement.
Which government entities are eligible applicants?
Eligible government applicants include state governments, county governments, city or township governments, and special district governments.
Are public or private universities eligible?
Yes. Public and state-controlled institutions of higher education and private institutions of higher education are listed as eligible applicants.
Are school districts eligible?
Yes. Independent school districts are listed as eligible applicants.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments are eligible, and tribal organizations that are not federally recognized governments are also listed as eligible applicants.
Are nonprofits eligible to apply?
Yes. Nonprofits are eligible, including both 501(c)(3) and non-501(c)(3) organizations (with the listing noting exclusions when specified for institutions of higher education).
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are eligible, and small businesses are also eligible.
Are public housing or Indian housing authorities eligible?
Yes. Public housing/Indian housing authorities are listed as eligible applicants.
Are minority-serving institutions included among eligible applicants?
Yes. The announcement specifically calls out multiple categories, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, and other similar institution types listed.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are called out as eligible applicant types.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are listed among additional eligible applicant types.
Are non-U.S. (foreign) organizations eligible?
Yes. Non-U.S. (foreign) organizations are explicitly listed as eligible.
Are regional organizations eligible?
Yes. Regional organizations are listed as eligible applicant types.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are listed as eligible applicant types.
What was the original closing date listed for this opportunity?
The original closing date is July 15, 2020.
What was the creation date for the listing?
The creation date is January 13, 2020.
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