Opportunity Information: Apply for RFA RM 23 002
The National Institutes of Health (NIH) released this funding opportunity announcement (FOA), RFA-RM-23-002, to fund an Integration and Coordination Center (ICC) for the Common Fund Data Ecosystem (CFDE). The ICC is meant to act as a program-wide connective hub that strengthens cohesion across the CFDE, helping the various participating efforts work together as a unified ecosystem rather than as separate projects. The FOA uses the U54 cooperative agreement mechanism (Clinical Trial Not Allowed), which signals that NIH expects substantial involvement from program staff in guiding, coordinating, and partnering with the awardee(s) as the work is carried out.
At its core, the ICC will support the CFDE by integrating relevant NIH Common Fund (CF) programs into the ecosystem and coordinating activities across other CFDE centers. This is not simply a technical integration role; it is also an organizational and strategic coordination function aimed at making the ecosystem more consistent, aligned, and usable for the broader research community. A key objective is to ensure that data and resources produced by Common Fund programs can be reused for new questions and new discoveries, which requires common approaches to organization, documentation, interoperability, and ongoing governance.
A major responsibility described in the FOA is to help Common Fund programs develop data sustainability plans. In practical terms, this means assisting programs in planning how their data, tools, and other digital resources will remain accessible, maintained, and usable beyond the initial period of funding. Sustainability planning typically involves considerations like long-term hosting, persistent identifiers, metadata quality, documentation, governance for updates, budgeting for maintenance, and aligning with community and NIH expectations for stewardship and reuse.
The ICC is also expected to drive continuous improvement through an annual evaluation program. That emphasis on routine evaluation suggests the center will need to establish measurable goals, track progress, gather feedback from stakeholders and users, identify gaps or friction points in how the ecosystem operates, and then coordinate corrective actions or refinements across CFDE components. The annual cadence implies this is intended to be a living ecosystem that iteratively improves rather than a one-time build.
NIH anticipates the awardee(s) will work collaboratively with each other and with other participating CFDE components to integrate and coordinate activities across the ecosystem. Because this is a cooperative agreement, coordination and communication are central to success: the ICC is positioned to convene stakeholders, facilitate alignment across centers, and help ensure that the ecosystem develops in a coherent way that serves end users.
The intended end product of the CFDE, supported by the ICC, is described as a thriving data ecosystem that enables broad reuse of Common Fund data and resources by the research community. That framing puts strong emphasis on downstream usability and impact: success is not just that data exist, but that they are findable, accessible, interoperable, and reusable in ways that accelerate research and support unanticipated secondary analyses.
Eligibility is broad and includes many domestic organization types: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; public housing authorities/Indian housing authorities; and Native American tribal governments (federally recognized) as well as Native American tribal organizations (other than federally recognized tribal governments). The FOA also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving institutions, HBCUs, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, Indian/Native American tribal governments (other than federally recognized), and US territories or possessions.
Foreign eligibility is limited. Non-domestic (non-US) entities (foreign organizations and foreign institutions) are not eligible to apply, and non-domestic components of US organizations are not eligible to apply. However, foreign components, as defined by the NIH Grants Policy Statement, are allowed, meaning a US-based applicant may include certain foreign elements in the project when justified and consistent with NIH policy.
The opportunity is categorized as discretionary funding, with a health funding activity category and CFDA number 93.310. The original application closing date listed for this FOA was June 28, 2023. The award ceiling and the expected number of awards were not specified in the provided source data.Apply for RFA RM 23 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Integration and Coordination Center for the Common Fund Data Ecosystem (U54 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310.
- This funding opportunity was created on 2023-03-24.
- Applicants must submit their applications by 2023-06-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): NIH RFA-RM-23-002 (CFDE Integration and Coordination Center)
1) What is this funding opportunity?
This is a National Institutes of Health (NIH) funding opportunity announcement (FOA) identified as RFA-RM-23-002. It supports an Integration and Coordination Center (ICC) for the Common Fund Data Ecosystem (CFDE).
2) What is the purpose of the CFDE Integration and Coordination Center (ICC)?
The ICC is intended to function as a program-wide connective hub for the CFDE. Its role is to strengthen cohesion across participating efforts so the CFDE operates as a unified ecosystem rather than a collection of separate projects.
3) What funding mechanism is being used?
The FOA uses the U54 cooperative agreement mechanism and is listed as Clinical Trial Not Allowed.
4) What does it mean that this is a cooperative agreement (U54)?
A cooperative agreement indicates that NIH expects substantial involvement from NIH program staff in guiding, coordinating, and partnering with the awardee(s) as the work is carried out. This structure emphasizes active collaboration and ongoing coordination during the project.
5) Is the ICC role mainly technical, or does it include coordination and strategy?
It includes both. The ICC is not described as only a technical integration function. It is also an organizational and strategic coordination function aimed at improving consistency, alignment, and usability of the ecosystem for the broader research community.
6) What are the core responsibilities of the ICC described in the FOA?
Based on the provided description, the ICC is expected to:
- Integrate relevant NIH Common Fund (CF) programs into the CFDE.
- Coordinate activities across other CFDE centers.
- Help ensure CFDE components work together cohesively as one ecosystem.
- Support approaches that enable reuse of Common Fund data and resources.
- Help CF programs develop data sustainability plans.
- Run an annual evaluation program to drive continuous improvement.
7) What does “integrating Common Fund programs into the ecosystem” mean in practice?
The FOA frames integration as enabling Common Fund-generated data and resources to become part of a coherent ecosystem. This implies common approaches to organization, documentation, interoperability, and governance so that data and resources can be reused for new questions and discoveries.
8) Why is coordination across CFDE centers emphasized so strongly?
The ICC is positioned as the connective hub that convenes stakeholders and facilitates alignment. Because NIH expects substantial involvement under a cooperative agreement, success depends heavily on communication, coordination, and shared direction across the CFDE.
9) What is meant by “data sustainability plans,” and what might they include?
The ICC is expected to help Common Fund programs develop plans for how their data, tools, and other digital resources will remain accessible, maintained, and usable beyond the initial funding period. The provided description notes that sustainability planning typically involves considerations such as:
- Long-term hosting
- Persistent identifiers
- Metadata quality
- Documentation
- Governance for updates
- Budgeting for maintenance
- Alignment with community and NIH expectations for stewardship and reuse
10) What is the annual evaluation program expected to do?
The ICC is expected to drive continuous improvement through an annual evaluation program. The description suggests this includes establishing measurable goals, tracking progress, gathering feedback from stakeholders and users, identifying gaps or friction points in ecosystem operations, and coordinating corrective actions or refinements across CFDE components.
11) Why is the evaluation described as annual?
An annual cadence signals that the CFDE is intended to be a living ecosystem that improves iteratively over time rather than a one-time build. The ICC is expected to support that continuous improvement cycle.
12) Who is the intended beneficiary or end user of this work?
The intended end product is a thriving data ecosystem that enables broad reuse of NIH Common Fund data and resources by the research community. The emphasis is on downstream usability and impact, meaning data should not only exist but be usable for unanticipated secondary analyses and new discoveries.
13) What is meant by broad reuse of Common Fund data and resources?
In the provided description, broad reuse means enabling data and resources produced by Common Fund programs to be reused for new questions and new discoveries. Achieving this requires common approaches to organization, documentation, interoperability, and governance.
14) What types of organizations are eligible to apply?
Eligibility is described as broad and includes many domestic (U.S.) organization types, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education)
- For-profit organizations (other than small businesses)
- Small businesses
- Public housing authorities / Indian housing authorities
- Native American tribal governments (federally recognized)
- Native American tribal organizations (other than federally recognized tribal governments)
15) Are any additional applicant categories explicitly highlighted as eligible?
Yes. The FOA explicitly highlights additional eligible applicant categories including:
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Hispanic-serving institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Faith-based or community-based organizations
- Regional organizations
- Eligible federal agencies
- Indian/Native American tribal governments (other than federally recognized)
- U.S. territories or possessions
16) Are foreign (non-U.S.) organizations eligible to apply directly?
No. Non-domestic (non-U.S.) entities, including foreign organizations and foreign institutions, are not eligible to apply. Non-domestic components of U.S. organizations are also not eligible to apply.
17) Are any foreign activities allowed at all?
Yes, limited foreign involvement may be allowed through foreign components as defined by the NIH Grants Policy Statement. This means a U.S.-based applicant may include certain foreign elements in the project when justified and consistent with NIH policy.
18) What is the funding category and CFDA number for this opportunity?
The opportunity is categorized as discretionary funding, with a health funding activity category, and the listed CFDA number is 93.310.
19) Are clinical trials allowed under this FOA?
No. The FOA is identified as Clinical Trial Not Allowed.
20) When was the original application closing date?
The original application closing date listed for this FOA was June 28, 2023.
21) How many awards will NIH make, and what is the award ceiling?
The award ceiling and the expected number of awards were not specified in the provided source information.
22) What does success look like for the ICC and CFDE, based on this description?
Success is framed as achieving a coherent, aligned ecosystem that supports broad reuse of Common Fund data and resources. The description emphasizes usability and impact, including making data and resources reusable for new questions and unanticipated secondary analyses, supported by integration, coordination, sustainability planning, and continuous (annual) evaluation.
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